Archive Awards

  • MAJOR GENERAL SAHEB SINGH SOKHEY AWARD
    • ICMR-Awards-citations-20011-12-028.jpg
      Dr AVINASH SONAWANE
      Subject :
      Year : 2011
    • Address

    Read More

    This award was instituted in 1988 in accordance with the will of Major General Saheb Singh Sokhey and is granted to a scientist for his outstanding contributions in the field of communicable diseases, significantly adding to the existing knowledge in the field. The award for 2011 is being jointly presented to Dr Avinash Sonawane, Associate Professor, School of Biotechnology, KIIT University, Bhubaneswar for the research work on 'Development of combinational antimicrobial peptide based therapy for the treatment of tuberculosis'. Dr Sonawane's work is focused on the identification of Mycobacterium tuberculosis glycoproteins as potential drug and vaccine targets, and to study the role of endogenously expressed antimicrobial peptides in antimycobacterial cellular immunity. The research work led to the identification of novel glycoproteins responsible for initiation of TB infection process and evasion of host cell innate immune responses. His work has shown that some of these glycoproteins can be used as drug and vaccine targets. To improve the therapy against tuberculosis he has synthesized new derivatives of endogenously expressed antimicrobial peptides using peptide engineering approach. These peptide derivatives are significantly more active, stable, and short as compared to parental peptides. These derivatives in combination with conventional antiTB drugs showed significantly higher my cobactericidal activity. To improve anti-TB drug delivery he has developed a quantum dot and nanoparticle based technology. Using this technology, he has shown that peptides and anti-TB composite molecules can be effectively delivered to my cobacterial niche inside the macrophages causing effective killing of intracellular my cobacteria. Dr Sonawane has been awarded with EMBO Fellowship, Swiss National Science Fellowship, Swedish Institute Fellowship and Japanese Society for Promotion of Science (JSPS) Fellowship for his contributions in the field of tuberculosis. He has published over 30 research papers in national and international journals. He has also filed one patent.
  • MAJOR GENERAL SAHEB SINGH SOKHEY AWARD
    • ICMR-Awards-citations-20011-12-026.jpg
      Dr SIMANTI DATTA
      Subject :
      Year : 2011
    • Address

    Read More

    This award was instituted in 1988 in accordance with the will of Major General Saheb Singh Sokhey and is granted to a scientist for his outstanding contributions in the field of communicable diseases, significantly adding to the existing knowledge in the field. The award for 2011 is being jointly presented to Dr Simanti Datta, Assistant Professor, Centre for Liver Research, School of Digestive and Liver Disease, Institute of Post Graduate Medical Education & Research, Kolkata for the research work on 'Studies on molecular mechanisms-particularly the hostvirus interactions in hepatitis B virus related liver disease'. Dr Datta's research work is focused on viral hepatitis particularly that is caused by hepatitis B virus (HBV) and encompasses basic virology of HBV, molecular pathogenesis of hepatitis B as well as anti-HBV therapy and management of antiviral drug resistance. The important contributions included identification of potential viral biomarkers for predicting the prognosis of hepatitis B e-antigen-negative chronic infection, proposing a new sub-genotype of HBV genotype D, studying the prevalence and distinctiveness of HBV in primitive tribal communities of India and determining the predictors of death and clinical events in HBV-related decompensated cirrhotic patients based on a retrospective-prospective inception cohort design. She has made significant contribution towards understanding the genetic diversity and pathogenic potentials of Indian Helicobacter pylori strains are a major cause of peptic ulcer disease and an early risk factor for gastric cancer. In addition, she was also involved in the development of a new genetic engineering technology, called recombineering that would facilitate rapid and precise in vivo genetic engineering in a wide range of bacteria including pathogenic Escherichia coli, Vibrio cholera, Mycobacterium tuberculosis, etc. Dr Datta has published over 30 research papers in national and international journals. She holds three U.S. patents and had received the Technology Transfer Award-2004 from the Center for Cancer Research, National Cancer Institute, USA.
  • ICMR PRIZE FOR BIOMEDICAL RESEARCH CONDUCTED IN UNDER-DEVELOPED AREAS
    • ICMR-Awards-citations-20011-12-024.jpg
      Dr KANGIAM REKHA DEVI
      Subject :
      Year : 2011
    • Address

    Read More

    The ICMR Prize for biomedical research conducted in underdeveloped areas was instituted by the Council in 1983 for scientists who have contributed significantly to any field of biomedical sciences and is granted for the work carried out in under developed areas of the country. The prize for 2011 is being presented to Dr Kangiam Rekha Devi, Scientist-D, ICMR-Regional Medical Research Centre, Dibrugarh for the research work on 'Studies on paragonimiasis in North-Eastern India'. Dr Rekha Devi has made significant contributions on various aspects of medically important lung flukes especially on their epidemiology, molecular taxonomy and phylogeny. Dr Rekha Devi has shown that in remote areas of Arunachal Pradesh it was possible to control paragonimiasis as evidenced by significant reduction in the prevalence of the lung fluke infections in adults as well as children of both the sexes. She has carried out surveys for detection of tuberculosis and paragonimiasis in the remote areas in North-Eastern India using cough as a simple indicator. Specifically, she has found a new foci of paragonimiasis in Arunachal Pradesh, Assam, Mizoram and Meghalaya as also three new genotypes of lung flukes occurring in Assam and Arunachal Pradesh belonging to Paragonimus westermani complex based on DNA sequencing and phylogenetic analysis. She has also incriminated P. heterotremus as a causative agent of human pulmonary paragonimiasis in Arunachal Pradesh and Assam. She has also developed two rodent models for P. westermani and P. heterotremus. These rodent models of pulmonary paragonimiasis are useful for screening new drugs against lung flukes and also for immunological studies. Recently the technology to develop a highly sensitive and specific enzyme-linked immunosorbent assay (ELISA) kit for the detection of human paragonimiasis has been developed which is being commercialized. Dr Rekha Devi has published 17 research papers in national and international journals.
  • ICMR PRIZE FOR BIOMEDICAL RESEARCH FOR SCIENTISTS BELONGING TO UNDER-PRIVILEGED COMMUNITIES
    • ICMR-Awards-citations-20011-12-022.jpg
      PROF. ANIL KUMAR
      Subject :
      Year : 2011
    • Address

    Read More

    The ICMR Prize for Biomedical Research for Scientists belonging to underprivileged communities was instituted by the Council in 1983 for scientists who have contributed significantly to any field of biomedical sciences and is granted to scientists belonging to under privileged communities. The prize for 2011 is being presented to Prof. Anil Kumar, Professor of Pharmacology, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Panjab University, Chandigarh for the research work on 'Neuropharmacologial investigation on various neuroprotective mechanisms for age related problems'. Prof. Kumar has developed various neuroprotective strategies for age and related problems particularly, Alzheimer, Huntington's disease, Parkinson's disease, stroke and post stroke depression, stress complications, and sleep related problems. Prof. Kumar explained the possible role of oxidative damage, neuroinflammatory, apoptotic, and mitochondrial dysfunction in the pathogenesis of these disease conditions. His research work highlights the potential role of various herbal antioxidants - phytopharmaceuticals- botanicals, neuroprotectants, and cyclooxygenase inhibitors against these diseases. Several antioxidants (naringin, carvedilol), cyclooxygenase inhibitors (resveratrol, nimesulide, naproxen, rofecoxib, celecoxib), and immunophyllines (FK 506, cyclosporins) and their possible novel mechanisms (GABAergic and nitric oxide modulation) have been explored. Prof. Kumar has published more than 90 research papers in national and international journals. Dr Kumar is a Member of the National Academy of Medical Sciences, New Delhi, as also a Member of the National Academy of Sciences, India, Allahabad.
  • ICMR KSHANIKA ORATION AWARD
    • ICMR-Awards-citations-20011-12-020.jpg
      DR ROSHAN BEHRAM COLAH
      Subject :
      Year : 2011
    • Address

    Read More

    The ICMR Kshanika Oration Award was instituted in 1977 by Dr K. N. Sen, former Professor of Medicine, School of Tropical Medicine, Kolkata to be awarded to an eminent woman scientist for her meritorious work carried out in any of the branches of biomedical sciences. The award for the year 2011 is being presented to Dr Roshan Behram Colah, Scientist-F, ICMR-National Institute of Immunohaematology, Mumbai for the research work on 'Assessment of the health burden of haemoglobinopathies in western India and developing cost effective approaches for prevention and management'. Dr Colah has contributed significantly in undertaking extensive epidemiological studies to determine the variable prevalence of the thalassemias in western India and evaluated the advantages and limitations of screening different population groups. She showed the importance of micro-mapping to determine the true burden of disease as also documented the advantages and disadvantages of different technologies for screening and diagnosis of the Beta thalassemias to determine the suitable approach in our multi-ethnic population. Prenatal diagnosis was offered to over 2000 couples so far and the birth of more than 500 babies with major disease prevented. A simple reverse dot blot hybridization approach which was developed for characterizing common Indian Beta thalassemia mutations and abnormal hemoglobins for first trimester prenatal diagnosis was transferred to various centres including few medical colleges to establish more centres for prenatal diagnosis of haemoglobinopathies in the country. She showed the benefits of hydroxyurea therapy in reducing the transfusion requirements in transfusion dependent Beta thalassemia intermedia patients and the role of genetic factors in determining the response to this therapy. Dr Colah has published over 200 papers in peer reviewed national and international journals.
  • DR.H.B.DINGLEY MEMORIAL AWARD (PAEDIATRICS)
    • ICMR-Awards-citations-20011-12-018.jpg
      DR DEEPAK BANSAL
      Subject :
      Year : 2011
    • Address

    Read More

    The Dr H.B. Dingley Memorial Award was Instituted in 1988 by Smt. Deepika Kumar in memory of her father, late Dr H.B. Dingley for Indian scientists for the outstanding contributions in the field of paediatrics. The award for the year 2011 is being jointly presented to Dr Deepak Bansal, Additional Professor, Pediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh for the research work on 'Outcome of chronic idiopathic thrombocytopenic purpura (ITP) in children'. There is paucity of data on the long-term outcome and the probability of remission in chronic ITP. Dr Bansal provided evidence favouring conservative management over drug therapy for chronic ITP in children. The predicted spontaneous remission rate with chronic ITP was 30 and 44 per cent at five and 10 years, respectively. Platelet count at diagnosis and the treatment administered did not influence remission outcomes. He showed that all children who had intracranial haemorrhage had severe thrombocytopaenia. The converse was, however, not true, that is, majority of children who had severe thrombocytopaenia had mild bleeds. The study provided evidence that the administration of long-term steroids and other immunosuppressive agents to all children with chronic ITP is unnecessary. It proved that children with chronic ITP have a reasonable chance of spontaneous remission. Dr Bansal has published 100 indexed publications in the field of paediatric hematology-oncology. He was awarded a citation and gold medal by Govt. of Punjab in recognition of his work in the field of oncology in 2005.
  • DR.H.B.DINGLEY MEMORIAL AWARD (PAEDIATRICS)
    • ICMR-Awards-citations-20011-12-016.jpg
      DR NIRAJ KUMAR SRIVASTAVA
      Subject :
      Year : 2011
    • Address

    Read More

    The Dr H.B. Dingley Memorial Award was Instituted in 1988 by Smt. Deepika Kumar in memory of her father, late Dr H.B. Dingley for Indian scientists for the outstanding contributions in the field of paediatrics. The award for the year 2011 is being jointly presented to Dr Niraj Kumar Srivastava, Scientific Pool Officer, Neurobiology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, for the research work on 'High resolution NMR based analysis of serum lipids in Duchenne muscular dystrophy patients and its possible diagnostic significance'. Dr Srivastava has made significant contributions to the field of 'muscular dystrophy' and 'brain tumour'. He performed the nuclear magnetic resonance (NMR) spectroscopy based lipid analysis in serum of patients with Duchenne muscular dystrophy (DMD). Proton NMR spectroscopy based quantitative comparison of serum lipid components, i.e. triglycerides, phospholipids, free cholesterol, cholesterol ester and total cholesterol showed no significant difference between positive and negative gene deletion in case of DMD patients. Lipid profile of the serum provides the consistent high levels of phospholipids and high phospholipids to cholesterol ratio that distinguishes DMD patients from healthy subjects. NMR spectroscopy based analysis of lipid constituents of the serum may cross the present barrier of gene mutation analysis and provide an efficient alternative diagnostic method of DMD. He also performed the NMR spectroscopy based investigation of brain tumours. NMR spectroscopy based lipid profiling of tissue, serum, and CSF of patients with primary brain tumours opens a new window into the differentiation and characterization of different types and grades of tumours. He has published six research papers in national and international journals including a book chapter.
  • BASANTI DEVI AMIR CHAND PRIZE
    • ICMR-Awards-citations-20011-12-014.jpg
      DR SANGITA MUKHOPADHAY
      Subject :
      Year : 2011
    • Address

    Read More

    The Basanti Devi Amir Chand Prize was the earliest instituted award of ICMR, founded in 1953 by late Major General Amir Chand for the significant research contributions made by scientists in the field of biomedical sciences. The award for the year 2011 is being presented to Dr Sangita Mukhopadhay, Staff Scientist-6, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, for the research work on 'Tuberculosis immunopathology and identification of novel drug targets'. Understanding the molecular mechanisms of tuberculosis pathophysiology is paramount for development of suitable drug targets and candidate TB vaccines to overcome the nuances of rapidly emerging drug resistant strains of Mycobacterium tuberculosis. Dr Mukhopadhyay has made seminal contributions to understand how some of the crucial effector signalling pathways in an immunogically educated host are hijacked by the tuberculosis pathogen to favour its persistence and survival. These findings have led to design better drugs and therapeutic interventions to treat tuberculosis patients. Her work ascribed novel functions to two unique PE - PPE family of M. tuberculosis proteins (PPE2 and PPE18) by which the bacilli can shut down host's defence processes and ushered promising antivirulence strategies and compounds targeting the PPE2 and PPE18 proteins for the treatment of tuberculosis. Dr Mukhopadhyay has found that the PPE2 protein contains signatures typically found in eukaryotic transcription factors that translocates to the host cell nucleus to inhibit nitric oxide production by binding to the regulatory elements in iNOS promoter. An international patent has been granted for establishing that PPE2 is a novel drug target in tuberculosis. She has also made significant contributions in discovering a novel signalling network by which PPE18 protein inhibits pro-inflammatory signalling and the protective T - helper - 1 (Th1) response by binding to TLR2 and modulating NF-B - rel-SOCS3 activity. Dr Mukhopadhyay is a Fellow of the National Academy of Sciences, India, Allahabad, and the Indian Academy of Sciences, Bengaluru. She has filed two patents and published 40 research papers in international journals of high impact factors.
  • AMRUT MODY UNICHEM PRIZE
    • ICMR-Awards-citations-20011-12-012.jpg
      PROF. DHEERAJ GUPTA
      Subject :
      Year : 2011
    • Address

    Read More

    The Amrut Mody Unichem Prize was instituted by Unichem Laboratories in 1985. This prize is awarded to a scientist for the research work carried out in the field of Gastroenterology-Cardiology-Neurology-Maternal & Child Health- Chest Diseases. The award for the year 2011 is being presented in the field of Chest Diseases to Prof. Dheeraj Gupta, Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, for the research work on 'Sarcoidosis'. Sarcoidosis is now increasingly being recognized in India. However, the oberwhelming presence of tuberculosis has traditionally made the clinicians hesitant to diagnose sarcoidosis with confidence. Dr Gupta has been studying various aspects of sarcoidosis for over 18 years now and have researched in broadly three aspects - diagnosis, clinical severity and pathogenesis, which have contributed to better understanding and awareness of this multi-system disease in our county. He has demonstrated the important role of transbronchial lung biopsy in obtaining lung tissue for such demonstration, since lungs are the most commonly involved organs in sarcoidosis. Subsequently, Dr Gupta described the visible endobronchial abnormalities in about 30 per cent patients and also the value of adding endobronchial biopsy to transbronchial biopsy increases the diagnostic yield of bronchoscopy by about 10 per cent. He has also investigated the role of modern techniques like EBUS in diagnosis of sarcoidosis and its role vis-a-vis conventional bronchoscopy. Dr Gupta has is a Fellow of the National Academy of Medical Sciences, New Delhi as also Fellow of a large member of Professional Societies. He has published over 290 papers in various journals.
  • ICMR KSHANIKA ORATION AWARD
    • citations-2009-10-010.jpg
      DR SANGITA MUKHOPADHYAY
      Subject :
      Year : 2009
    • Address

    Read More

    The ICMR Kshanika Oration Award was instituted in 1977 by Dr K. N. Sen, former Professor of Medicine, School of Tropical Medicine, Kolkata to be awarded to an eminent woman scientist for her meritorious work carried out in any of the branches of Biomedical Sciences. The award for the year 2009 is being presented to Dr Sangita Mukhopadhyay, Staff Scientist-5, Chief, Laboratory of Molecular Cell Biology, Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad for her research work on 'Reactive oxygen species (ROS): Induction of immunesuppression during infection and ageing and Implication of anti - oxidants as therapeutic approaches'. ROS, generated during the innate immune response are considered to be important anti-microbial agents. However, in exceptional cases like tuberculosis overproduction of ROS 'per se' do not kill Mycobacterium bacilli but rather are involved in exacerbating the disease, which hint that ROS may actually favor pathogen survival by directly suppressing host's immune responses. Research in this area by Dr Mukhopadhyay reveals that excessive free radical generated in our body during chronic infections and other patho-physiological disorders like aging and stress can directly hamper our protective immune response by inhibiting interleukin-12 cytokine and downregulating T-helper 1 (Th1) T cell response and trigger immunosuppression. She has also made significant contributions in discovering a novel signalling network that regulate NF- B - rel activity and the stress response involving the SOCS3 protein. She has demonstrated that intracellular pathogen like M. tuberculosis exploits this signaling pathway to inhibit the anti - mycobacterial protective response to suit its intracellular life style. Dr Mukhopadhyay is a Fellow of the National Academy of Sciences India, Allahabad, and the Indian Academy of Sciences, Bangalore. She has filed three patents and published over 34 research papers in international journals.

Pages

Back to Top